WO2026022744 - HIGH-DURABILITY GLYCOSAMINOGLYCAN GELS AND METHODS OF MAKING THE SAME
National phase entry is expected:
Publication Number
WO/2026/022744
Publication Date
29.01.2026
International Application No.
PCT/IB2025/057489
International Filing Date
23.07.2025
Title **
[English]
HIGH-DURABILITY GLYCOSAMINOGLYCAN GELS AND METHODS OF MAKING THE SAME
[French]
GELS DE GLYCOSAMINOGLYCANE À DURABILITÉ ÉLEVÉE ET LEURS PROCÉDÉS DE FABRICATION
Applicants **
GALDERMA HOLDING SA
Inventors
KANDELIN, Lina
BERGMAN, Kristoffer
Priority Data
63/674,969
24.07.2024
US
Application details
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3935 | |
| EPO | Filing, Examination, Granting | 59283 | |
| Japan | Filing, Examination, Granting | 4091 | |
| South Korea | Filing, Examination, Granting | 5670 | |
| USA | Filing, Examination, Granting | 19340 |
Total:
92,319
Abstract[English]
Disclosed are durable polysaccharide compositions comprising GAGs covalently crosslinked with a carbohydrate crosslinker, and methods of making the same. GAG hydrogels according to the present disclosure have a molecular weight of at least 1.5 MDa, crosslinked by a crosslinker forming amide bonds with the GAG backbone and an elastic modulus (G') of less than or equal to 200 Pa. Further described are methods of using the durable polysaccharide compositions for treating skin (e.g., in reparative or plastic surgery, esthetic dermatology, facial contouring, body contouring, or gingival augmentation).[French]
Sont divulgués des compositions de polysaccharide durables comprenant des GAG réticulés de manière covalente avec un agent de réticulation glucidique, et leurs procédés de fabrication. Les hydrogels GAG selon la présente divulgation présentent un poids moléculaire d'au moins 1,5 MDa, réticulé par un agent de réticulation formant des liaisons amide avec le squelette GAG et un module élastique (G') inférieur ou égal à 200 Pa. L'invention concerne en outre des procédés d'utilisation des compositions de polysaccharide durables pour le traitement de la peau (par exemple, en chirurgie réparatrice ou plastique, en dermatologie esthétique, en remodelage facial, en remodelage corporel ou en augmentation gingivale).