WO2026013650 - RADIOLABELED STYRYLPYRIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF

National phase entry is expected:
Publication Number WO/2026/013650
Publication Date 15.01.2026
International Application No. PCT/IB2025/057108
International Filing Date 14.07.2025
Title **
[English] RADIOLABELED STYRYLPYRIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF
[French] STYRYLPYRIDINES RADIOMARQUÉES ET COMPOSITIONS PHARMACEUTIQUES ASSOCIÉES
Applicants **
JUBILANT DRAXIMAGE, INC.
Inventors
KULANGARA, Vijayaraj Kuniyil
PRASAD, M Umamaheshwar
NANDI, Indranil
SARWAL, Dinesh Kumar
PANNU, Kamaljeet
Priority Data
63/670,611   12.07.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2267
EPO Filing, Examination, Granting14203
Japan Filing, Examination, Granting2325
South Korea Filing, Examination, Granting2441
USA Filing, Examination, Granting4740
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Abstract[English] The invention discloses radiopharmaceutical composition of Fluorine-18 (F18) labelled styrylpyridine compounds, for use as a medicament for the treatment or diagnosis of a disease or condition associated with build-up of amyloid-β (Aβ) aggregates. The invention further relates to polymorphic forms of precursors of F18 Florbetapir and their use for preparing F18 Florbetapir.[French] L'invention concerne une composition radiopharmaceutique de composés de styrylpyridine marqués au fluor-18 (F18), destinée à être utilisée en tant que médicament pour le traitement ou le diagnostic d'une maladie ou d'un état associé à l'accumulation d'agrégats de bêta-amyloïde (Abêta). L'invention concerne en outre des formes polymorphes de précurseurs de F18 Florbetapir et leur utilisation pour préparer F18 Florbetapir.

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