WO2025262623 - METHOD OF TREATING HBV/HIV COINFECTION

National phase entry is expected:
Publication Number WO/2025/262623
Publication Date 26.12.2025
International Application No. PCT/IB2025/056231
International Filing Date 18.06.2025
Title **
[English] METHOD OF TREATING HBV/HIV COINFECTION
[French] MÉTHODE DE TRAITEMENT D'UNE COINFECTION PAR VHB/VIH
Applicants **
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
Inventors
PAFF, Melanie T.
THEODORE, Dickens
HEZAREH, Marjan
BOURNE, Eric J.
DOLMAN, Grace E.
Priority Data
63/662,597   21.06.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3062
EPO Filing, Examination, Granting27253
Japan Filing, Examination, Granting3291
South Korea Filing, Examination, Granting4252
USA Filing, Examination, Granting13340
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Total: 51,198
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Abstract[English] The present disclosure is related to methods for treating chronic hepatitis B infection in a human having HBV/HIV coinfection. The methods comprise administering to a human having HBV/HIV coinfection a therapeutically effective amount of an antisense oligonucleotide (ASO), wherein the subject has a HBsAg baseline level of not greater than a threshold level.[French] La présente divulgation concerne des méthodes de traitement d'une infection chronique par l'hépatite B chez un être humain ayant une coinfection par VHB/VIH. Les méthodes comprennent l'administration à un être humain ayant une co-infection par VHB/VIH d'une quantité thérapeutiquement efficace d'un oligonucléotide antisens (ASO), le sujet ayant un niveau de base de HBsAg non supérieur à un niveau seuil.

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