WO2025243239 - PROCESS FOR DETECTION OF FETAL CELLS
National phase entry is expected:
Publication Number
WO/2025/243239
Publication Date
27.11.2025
International Application No.
PCT/IB2025/055310
International Filing Date
22.05.2025
Title **
[English]
PROCESS FOR DETECTION OF FETAL CELLS
[French]
PROCÉDÉ DE DÉTECTION DE CELLULES FŒTALES
Applicants **
MENARINI SILICON BIOSYSTEMS S.P.A.
Inventors
DOFFINI, Anna
MARANTA, Chiara
MANGANO, Chiara
GIOVANNONE, Emilia Dora
MUSCI, Thomas J.
Priority Data
102024000011620
22.05.2024
IT
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3649 | |
| EPO | Filing, Examination, Granting | 46948 | |
| Japan | Filing, Examination, Granting | 3769 | |
| South Korea | Filing, Examination, Granting | 5169 | |
| USA | Filing, Examination, Granting | 15740 |
Total:
75,275
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Abstract[English]
Provided herein is a method of isolating fetal cells from a sample from a pregnant subject. The method utilizes magnetic particles conjugated to anti-EGFR or a combination of anti-EGFR and anti-CD105 antibodies to create an enriched sample and then labeled antibodies for fetal cell markers to isolate different fetal cell types in the sample from the pregnant subject. Said isolated fetal cells can then be analyzed via gene sequencing or genomic or genetic analysis.[French]
La présente invention concerne un procédé d'isolement de cellules fœtales à partir d'un échantillon prélevé sur un sujet enceinte. Le procédé utilise des particules magnétiques conjuguées à des anticorps anti-EGFR ou à une combinaison d'anticorps anti-EGFR et anti-CD105 pour créer un échantillon enrichi, puis des anticorps marqués pour que des marqueurs de cellules fœtales isolent différents types de cellules fœtales dans l'échantillon prélevé sur le sujet enceinte. Lesdites cellules fœtales isolées peuvent ensuite être analysées par séquençage génique ou par analyse génomique ou génétique.