WO2025243237 - COMBINATION PROCESS FOR DETECTION OF FETAL CELLS

National phase entry is expected:
Publication Number WO/2025/243237
Publication Date 27.11.2025
International Application No. PCT/IB2025/055307
International Filing Date 22.05.2025
Title **
[English] COMBINATION PROCESS FOR DETECTION OF FETAL CELLS
[French] PROCÉDÉ DE COMBINAISON POUR LA DÉTECTION DE CELLULES FŒTALES
Applicants **
MENARINI SILICON BIOSYSTEMS S.P.A.
Inventors
DOFFINI, Anna
MARANTA, Chiara
MANGANO, Chiara
GIOVANNONE, Emilia Dora
MUSCI, Thomas J.
Priority Data
102024000011632   22.05.2024   IT
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2544
EPO Filing, Examination, Granting17402
Japan Filing, Examination, Granting2731
South Korea Filing, Examination, Granting3174
USA Filing, Examination, Granting7340
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Total: 33,191
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Abstract[English] Provided herein is a method of isolating fetal cells from a sample from a pregnant subject. The method utilizes magnetic particles conjugated to anti-EGFR and anti-HER2 antibodies to create an enriched sample and then labeled antibodies for fetal cell markers to isolate different fetal cell types in the sample from the pregnant subject. Said isolated fetal cells can then be analyzed via gene sequencing or genomic or genetic analysis.[French] L'invention concerne un procédé d'isolement de cellules fœtales à partir d'un échantillon prélevé sur un sujet enceinte. Le procédé utilise des particules magnétiques conjuguées à des anticorps anti-EGFR et anti-HER2 pour créer un échantillon enrichi, puis des anticorps marqués pour que les marqueurs de cellules fœtales isolent différents types de cellules fœtales dans l'échantillon prélevé sur le sujet enceinte. Lesdites cellules fœtales isolées peuvent ensuite être analysées par séquençage génique ou par analyse génomique ou génétique.

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