WO2025243213 - IMPROVING STEM CELL DIFFERENTIATION POTENCY USING SIMULATED MICROGRAVITY
National phase entry is expected:
Publication Number
WO/2025/243213
Publication Date
27.11.2025
International Application No.
PCT/IB2025/055253
International Filing Date
21.05.2025
Title **
[English]
IMPROVING STEM CELL DIFFERENTIATION POTENCY USING SIMULATED MICROGRAVITY
[French]
AMÉLIORATION DE LA PUISSANCE DE DIFFÉRENCIATION DE CELLULES SOUCHES À L'AIDE D'UNE MICROGRAVITÉ SIMULÉE
Applicants **
NEW YORK UNIVERSITY IN ABU DHABI CORPORATION
Inventors
TEO, Jeremy
SAPUDOM, Jiranuwat
Priority Data
63/651,916
24.05.2024
US
Application details
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International Searching Authority |
MOIP
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2561 | |
| EPO | Filing, Examination, Granting | 14978 | |
| Japan | Filing, Examination, Granting | 2285 | |
| South Korea | Filing, Examination, Granting | 1830 | |
| USA | Filing, Examination, Granting | 4740 |

Total:
26,394
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Abstract[English]
The present disclosure provides methods for improving the differentiation potency using simulated microgravity. The improvement in differentiation is relative to stem cells that are cultured at 1 g (i.e., at Earth's gravity). In various examples, the improvement is at least 2x better than cultures relative to stem cells that are cultured at 1 g. Also disclosed are methods of differentiating cells cultured by the methods described herein.[French]
La présente divulgation concerne des procédés pour améliorer la puissance de différenciation à l'aide d'une microgravité simulée. L'amélioration de la différenciation est relative à des cellules souches cultivées à 1 g (c'est-à-dire à la gravité terrestre). Dans divers exemples, l'amélioration est au moins 2x meilleure que les cultures par rapport aux cellules souches qui sont cultivées à 1 g. Sont également divulgués des procédés de différenciation de cellules cultivées par les procédés décrits ici.