WO2025229492 - OREXIN TYPE 2 RECEPTOR AGONIST MICROCAPSULES FOR SUSTAINED RELEASE DOSING

National phase entry is expected:
Publication Number WO/2025/229492
Publication Date 06.11.2025
International Application No. PCT/IB2025/054393
International Filing Date 28.04.2025
Title **
[English] OREXIN TYPE 2 RECEPTOR AGONIST MICROCAPSULES FOR SUSTAINED RELEASE DOSING
[French] MICROCAPSULES AGONISTES DU RÉCEPTEUR DE TYPE 2 DE L'OREXINE POUR DOSAGE À LIBÉRATION PROLONGÉE
Applicants **
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventors
MANOSHIRO, Tomoyuki
BABA, Ayako
KARUBE, Hiromitsu
MURATA, Naoyuki
Priority Data
63/640,118   29.04.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2338
EPO Filing, Examination, Granting10558
Japan Filing, Examination, Granting2262
South Korea Filing, Examination, Granting2236
USA Filing, Examination, Granting4740
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Total: 22,134
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Abstract[English] The present disclosure provides a controlled release composition comprising an orexin type 2 receptor agonist or a salt or hydrate thereof and a lactic acid-glycolic acid polymer or salt thereof; wherein the composition is in the form of microcapsules. The present disclosure also provides methods of making such controlled release compositions and methods of using the controlled release compositions.[French] La présente divulgation concerne une composition à libération contrôlée comprenant un agoniste du récepteur de l'orexine de type 2 ou un sel ou un hydrate de celui-ci et un polymère d'acide lactique-acide glycolique ou un sel de celui-ci ; la composition se présentant sous la forme de microcapsules. La présente invention concerne également des procédés de fabrication de telles compositions à libération contrôlée et des procédés d'utilisation des compositions à libération contrôlée.

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