WO2025224605 - SEQUENTIAL ADMINISTRATION OF ANTI-MELANOMA VACCINE AND ANTI-PD-1 MONOCLONAL ANTIBODIES

National phase entry is expected:
Publication Number WO/2025/224605
Publication Date 30.10.2025
International Application No. PCT/IB2025/054161
International Filing Date 21.04.2025
Title **
[English] SEQUENTIAL ADMINISTRATION OF ANTI-MELANOMA VACCINE AND ANTI-PD-1 MONOCLONAL ANTIBODIES
[French] ADMINISTRATION SÉQUENTIELLE D'UN VACCIN ANTI-MÉLANOME ET D'ANTICORPS MONOCLONAUX ANTI-PD-1
Applicants **
CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET)
FUNDACIÓN SALES
ARIS, Mariana
Inventors
MORDOH, José
BARRIO, María Marcela
SCHWAB, Erika
BRAVO, Alicia Inés
Priority Data
63/637,463   23.04.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2427
EPO Filing, Examination, Granting13291
Japan Filing, Examination, Granting2462
South Korea Filing, Examination, Granting2595
USA Filing, Examination, Granting5540
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Total: 26,315
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Abstract[English] Methods for enhancing an anti-tumor immune response to treatment in a subject who has cutaneous melanoma (CM). In particular, the subject is treated with anti-PD-1 monoclonal antibodies (MAbs) following treatment with a vaccine generating an immune response against antigens of CM cells.[French] L'invention concerne des méthodes pour améliorer une réponse immunitaire antitumorale à un traitement chez un sujet atteint d'un mélanome cutané (MC). En particulier, le sujet est traité avec des anticorps monoclonaux (MAb) anti-PD-1 après traitement avec un vaccin générant une réponse immunitaire contre des antigènes de cellules de MC.

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