WO2025224598 - HER2 TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF

National phase entry is expected:
Publication Number WO/2025/224598
Publication Date 30.10.2025
International Application No. PCT/IB2025/054153
International Filing Date 21.04.2025
Title **
[English] HER2 TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF
[French] PEPTIDES CYCLIQUES CIBLANT HER2 ET CONJUGUÉS ASSOCIÉS
Applicants **
NOVARTIS AG
Inventors
CLEMENTE, Gonçalo dos Santos
EHARA, Takeru
FELBER, Richard
FISCHER, Matteo
GAUTER, Francois
KARPOV, Alexei
LACAUD-BAUMLIN, Marion
MALO, Rafael Bermeo
MARZINZIK, Andreas
MIZUKOSHI, Yoshihide
PARK, Danielle
RESCHKE, Markus Oliver
RIPOCHE, Sebastien
SCHAEFER, Michael
STACHYRA, Therese-Marie
UEDA, Kyosuke
ZUEGER, Patrik Peter
Priority Data
63/637,572   23.04.2024   US
63/760,270   19.02.2025   US
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting9773
EPO Filing, Examination, Granting90873
Japan Filing, Examination, Granting4473
South Korea Filing, Examination, Granting6681
USA Filing, Examination, Granting40740
MasterCard Visa
Total: 152,540
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Abstract[English] Described herein are cyclic peptides targeting human epidermal growth factor receptor 2 (HER2), and their incorporation into compounds for radioligand imaging and therapies, as well as methods and/or uses of such compounds for the imaging, treatment and/or prevention of HER2-implicated diseases and disorders (e.g., cancer).[French] L'invention concerne des peptides cycliques ciblant le récepteur 2 du facteur de croissance épidermique humain (HER2), et leur incorporation dans des composés pour l'imagerie et les thérapies par radioligands, ainsi que des méthodes et/ou des utilisations de tels composés pour l'imagerie, le traitement et/ou la prévention de maladies et de troubles impliquant HER2 (par exemple, le cancer).

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