WO2025219955 - SOLUBLE TCRS AND METHODS OF USE THEREOF

National phase entry is expected:
Publication Number WO/2025/219955
Publication Date 23.10.2025
International Application No. PCT/IB2025/054084
International Filing Date 17.04.2025
Title **
[English] SOLUBLE TCRS AND METHODS OF USE THEREOF
[French] TCR SOLUBLES ET LEURS MÉTHODES D'UTILISATION
Applicants **
BIONTECH SE
Inventors
SROUJI, John
LUOMA, Adrienne
DULBERGER, Charles Lefco
GRAY, Justin
BIRTEL, Matthias
KAISER, Andrew D.M.
Priority Data
63/635,216   17.04.2024   US
63/721,039   15.11.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting13183
EPO Filing, Examination, Granting403365
Japan Filing, Examination, Granting6200
South Korea Filing, Examination, Granting20743
USA Filing, Examination, Granting74240
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Abstract[English] The present disclosure provides a therapy with soluble T cell receptors (TCRs) and cells comprising chimeric antigen receptors (CAR) including compositions, polynucleotides encoding the compositions and methods of use thereof. The methods and compositions provided herein can be used for the treatment of cancer.[French] La présente divulgation concerne une thérapie à base de récepteurs de lymphocytes T (TCR) solubles et des cellules comprenant des récepteurs antigéniques chimériques (CAR) y compris des compositions, des polynucléotides codant pour les compositions et leurs méthodes d'utilisation. Les méthodes et les compositions de la divulgation peuvent être utilisées pour le traitement du cancer.

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