WO2025219924 - CELL LINES OVEREXPRESSING VESICULAR STOMATITIS VIRUS G

National phase entry is expected:
Publication Number WO/2025/219924
Publication Date 23.10.2025
International Application No. PCT/IB2025/054035
International Filing Date 17.04.2025
Title **
[English] CELL LINES OVEREXPRESSING VESICULAR STOMATITIS VIRUS G
[French] LIGNÉES CELLULAIRES SUREXPRIMANT LE VIRUS DE LA STOMATITE VÉSICULAIRE G
Applicants **
CSL BEHRING LLC
Inventors
KLIMPEL, Maximillian
LAUX, Holger
Priority Data
63/636,201   19.04.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3325
EPO Filing, Examination, Granting27917
Japan Filing, Examination, Granting3083
South Korea Filing, Examination, Granting3987
USA Filing, Examination, Granting13310
MasterCard Visa
Total: 51,622
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Abstract[English] The present disclosure generally relates to the manufacturing of gene therapy products, and specifically to methods of producing an enveloped virus from a stable producer cell clone or a stable producer cell pool overexpressing vesicular stomatitis virus G (VSV-G) in suspension cell culture.[French] La présente invention concerne de manière générale la fabrication de produits de thérapie génique, et plus particulièrement des procédés de production d'un virus enveloppé à partir d'un clone de cellule productrice stable ou d'un groupe de cellules productrices stables surexprimant le virus de la stomatite vésiculaire G (VSV-G) dans une culture cellulaire en suspension.

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