WO2025219920 - METHODS OF PRODUCING AN ENVELOPED VIRUS
National phase entry is expected:
Publication Number
WO/2025/219920
Publication Date
23.10.2025
International Application No.
PCT/IB2025/054027
International Filing Date
17.04.2025
Title **
[English]
METHODS OF PRODUCING AN ENVELOPED VIRUS
[French]
PROCÉDÉS DE PRODUCTION D'UN VIRUS ENVELOPPÉ
Applicants **
CSL BEHRING LLC
Inventors
KLIMPEL, Maximillian
LAUX, Holger
Priority Data
63/636,283
19.04.2024
US
Application details
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International Searching Authority |
USPTO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3573 | |
| EPO | Filing, Examination, Granting | 39549 | |
| Japan | Filing, Examination, Granting | 3476 | |
| South Korea | Filing, Examination, Granting | 4857 | |
| USA | Filing, Examination, Granting | 12310 |
Total:
63,765
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Abstract[English]
The present disclosure relates generally to the manufacturing of gene therapy products, and specifically to methods of producing an enveloped virus in a suspension perfusion cell culture comprising filtering the cell culture fluid through a filter at a harvest rate of at least 2 vessel volumes per day (VVD) to produce a filtered cell culture 5 fluid comprising the enveloped virus, wherein the filter retains cells from the suspension cell line.[French]
La présente divulgation concerne de manière générale la fabrication de produits de thérapie génique et, spécifiquement, des procédés de production d'un virus enveloppé dans une culture cellulaire de perfusion en suspension comprenant le filtrage du fluide de culture cellulaire dans un filtre à un taux de récolte d'au moins 2 volumes de récipient par jour (VVD) pour produire un fluide de culture cellulaire filtré comprenant le virus enveloppé, le filtre retenant les cellules de la lignée cellulaire en suspension.