WO2025215515 - SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS

National phase entry is expected:
Publication Number WO/2025/215515
Publication Date 16.10.2025
International Application No. PCT/IB2025/053672
International Filing Date 07.04.2025
Title **
[English] SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS
[French] SYSTÈMES ET PROCÉDÉS DE GÉNÉRATION DE MATÉRIAUX HYPERPOLARISÉS
Applicants **
NVISION IMAGING TECHNOLOGIES GMBH
Inventors
SCHWARTZ, Ilai
KEIM, Michael
RÖSLER, Lorenz
GIERSE, Martin
KNECHT, Stephan
Priority Data
63/631,096   08.04.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4745
EPO Filing, Examination, Granting81577
Japan Filing, Examination, Granting4566
South Korea Filing, Examination, Granting6836
USA Filing, Examination, Granting19140
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Total: 116,864
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Abstract[English] The disclosed embodiments include systems and methods for producing hyperpolarized molecules of interest (such as hyperpolarized biorelevant imaging agents), in clinically relevant polarizations, concentrations, volumes, and purity. Disclosed embodiments provide technical improvements in polarizing molecules of interest in solution. These technical improvements support increases in molecule of interest concentration and the degree of polarization.[French] Les modes de réalisation de l'invention comprennent des systèmes et des procédés de production de molécules d'intérêt hyperpolarisées (telles que des agents d'imagerie biopertinents hyperpolarisés), dans des polarisations, des concentrations, des volumes et une pureté cliniquement pertinents. Des modes de réalisation de l'invention concernent des améliorations techniques dans des molécules polarisantes d'intérêt en solution. Ces améliorations techniques prennent en charge des augmentations de la concentration de molécules d'intérêt et du degré de polarisation.

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