WO2025210521 - LIPID NANOPARTICLES FOR STIMULATING T CELLS
National phase entry is expected:
Publication Number
WO/2025/210521
Publication Date
09.10.2025
International Application No.
PCT/IB2025/053436
International Filing Date
02.04.2025
Title **
[English]
LIPID NANOPARTICLES FOR STIMULATING T CELLS
[French]
NANOPARTICULES LIPIDIQUES POUR STIMULER DES LYMPHOCYTES T
Applicants **
GENEVANT SCIENCES GMBH
Inventors
DALY, Owen
SCHREINER, Petra
LAM, Kieu
HEYES, James
Priority Data
63/574,479
04.04.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 4685 | |
| EPO | Filing, Examination, Granting | 80114 | |
| Japan | Filing, Examination, Granting | 4531 | |
| South Korea | Filing, Examination, Granting | 6742 | |
| USA | Filing, Examination, Granting | 22540 |
Total:
118,612
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Abstract[English]
The present disclosure provides lipid nanoparticles that are particularly beneficial in inducing an immune response in a subject, particularly by stimulating CD8+ T cells associated with protein or protein fragments of interest. The lipid nanoparticles can have a negative zeta potential and/or particular configurations and/or relative amounts of a phospholipid, an ionizable lipid, and a conjugated lipid. The disclosure also provides vaccines, other pharmaceutical compositions, and methods including the provided lipid nanoparticles.[French]
La présente divulgation propose des nanoparticules lipidiques qui sont particulièrement bénéfiques pour induire une réponse immunitaire chez un sujet, en particulier par stimulation de lymphocytes T CD8+ associés à une protéine ou des fragments protéiques d'intérêt. Les nanoparticules lipidiques peuvent présenter un potentiel zêta négatif et/ou des configurations particulières et/ou des quantités relatives d'un phospholipide, d'un lipide ionisable et d'un lipide conjugué. La divulgation propose également des vaccins, d'autres compositions pharmaceutiques et des procédés comprenant les nanoparticules lipidiques proposées.