WO2025202985 - PROCESS FOR THE PREPARATION AND PURIFICATION OF CRYSTALLINE RESMETIROM

National phase entry is expected:
Publication Number WO/2025/202985
Publication Date 02.10.2025
International Application No. PCT/IB2025/053291
International Filing Date 28.03.2025
Title **
[English] PROCESS FOR THE PREPARATION AND PURIFICATION OF CRYSTALLINE RESMETIROM
[French] PROCÉDÉ DE PRÉPARATION ET DE PURIFICATION DE RESMÉTIROM CRISTALLIN
Applicants **
MOREPEN LABORATORIES LIMITED
Inventors
TANWAR, Madan Pal
VERMA, Gian Chand
SURI, Sanjay
Priority Data
202411025945   29.03.2024   IN
202411046749   18.06.2024   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2069
EPO Filing, Examination, Granting11606
Japan Filing, Examination, Granting2080
South Korea Filing, Examination, Granting1952
USA Filing, Examination, Granting7140
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Total: 24,847
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Abstract[English] The present invention relates to an efficient process for the preparation and purification of crystalline resmetirom. More specifically, the present invention relates to an operationally simple process for controlling/limiting the interference of impurities in purity of the crystalline resmetirom in accordance with ICH guidelines. Further, the present invention relates to an efficient process for the preparation of resmetirom Form I.[French] La présente invention concerne un procédé efficace pour la préparation et la purification de resmétirom cristallin. Plus particulièrement, la présente invention concerne un procédé fonctionnellement simple pour contrôler les impuretés ou limiter leur aptitude à interférer avec la pureté du resmétirom crisallin conformément à des directives ICH. En outre, la présente invention concerne un procédé efficace pour la préparation de resmétirom de forme I.

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