WO2025196724 - METHODS FOR INDUCING IMMUNE RESPONSES
National phase entry is expected:
Publication Number
WO/2025/196724
Publication Date
25.09.2025
International Application No.
PCT/IB2025/053017
International Filing Date
21.03.2025
Title **
[English]
METHODS FOR INDUCING IMMUNE RESPONSES
[French]
MÉTHODES POUR INDUIRE DES RÉPONSES IMMUNITAIRES
Applicants **
MOAT BIOTECHNOLOGY CORPORATION
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventors
ROTHER, Russell
BARRY, Michael A.
Priority Data
63/568,220
21.03.2024
US
Application details
| Total Number of Claims/PCT | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 4982 | |
| EPO | Filing, Examination, Granting | 52330 | |
| Japan | Filing, Examination, Granting | 3755 | |
| South Korea | Filing, Examination, Granting | 5201 | |
| USA | Filing, Examination, Granting | 15890 |
Total:
82,158
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Abstract[English]
Provided are methods for inducing immune responses against pathogens in a mammal. The methods comprise administering a single cycle adenovirus (SC-Ad) comprising a nucleic acid sequence encoding an immunogen of said pathogen to said mammal. The SC-Ad is administered by inhalation and infects a cell of said mammal, thereby causing expression of said immunogen leading to the induction of said immune response. New infectious virions are not produced. The methods may be of particular utility in vaccination for respiratory pathogens. Corresponding medical uses of the SC-Ads are also provided.[French]
L'invention concerne des méthodes pour induire des réponses immunitaires contre des pathogènes chez un mammifère. Les méthodes comprennent l'administration d'un adénovirus à cycle unique (SC-Ad) comprenant une séquence d'acide nucléique codant pour un immunogène dudit pathogène audit mammifère. Le SC-Ad est administré par inhalation et infecte une cellule dudit mammifère, provoquant ainsi l'expression dudit immunogène conduisant à l'induction de ladite réponse immunitaire. De nouveaux virions infectieux ne sont pas produits. Les méthodes peuvent être particulièrement utiles dans la vaccination contre des pathogènes respiratoires. L'invention concerne également des utilisations médicales correspondantes des SC-Ad.