WO2025169163 - METHOD FOR THE SYNTHESIS OF TROFINETIDE AND ITS ANALOGUES
National phase entry is expected:
Publication Number
WO/2025/169163
Publication Date
14.08.2025
International Application No.
PCT/IB2025/051364
International Filing Date
10.02.2025
Title **
[English]
METHOD FOR THE SYNTHESIS OF TROFINETIDE AND ITS ANALOGUES
[French]
PROCÉDÉ DE SYNTHÈSE DE TROFINÉTIDE ET DE SES ANALOGUES
Applicants **
TEADUS PHARMA PRIVATE LIMITED
REVA UNIVERSITY
Inventors
AVULA, Veeranjaneyulu
BALARAMAN, Selvakumar
SIRIPURAPU, Umamaheswar
D N, Akshitha
G, Nagendra
M, Ranjithkumar
H, Surya Prakash Rao
Priority Data
202441009099
10.02.2024
IN
Application details
| Total Number of Claims/PCT | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
IP India
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1954 | |
| EPO | Filing, Examination, Granting | 11565 | |
| Japan | Filing, Examination, Granting | 1892 | |
| South Korea | Filing, Examination, Granting | 1524 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
21,675
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Abstract[English]
The present invention relates to a method for the synthesis of Trofinetide (1) and its analogues The present invention further relates to a novel approach for the synthesis of Trofinetide (1) and its analogues through TAG approach by sequential amino acid coupling using solid-phase peptide synthesis. The patent also relates to a commercially viable purification method for the synthesis of highly pure Trofinetide (1) and its analogues. Formula (1)[French]
La présente invention concerne un procédé de synthèse de trofinétide (1) et de ses analogues. La présente invention concerne également une nouvelle approche pour la synthèse de trofinétide (1) et de ses analogues par approche TAG par couplage séquentiel d'acides aminés à l'aide d'une synthèse peptidique en phase solide. L'invention concerne en outre un procédé de purification commercialement viable pour la synthèse de trofinétide (1) de haute pureté et de ses analogues. Formule (1)