WO2025146672 - AN IMPROVED METHOD FOR SEPARATION AND QUANTIFICATION OF PANCREATIC ENZYMES BY USING CE-SDS

National phase entry is expected:
Publication Number WO/2025/146672
Publication Date 10.07.2025
International Application No. PCT/IB2025/050122
International Filing Date 06.01.2025
Title **
[English] AN IMPROVED METHOD FOR SEPARATION AND QUANTIFICATION OF PANCREATIC ENZYMES BY USING CE-SDS
[French] PROCÉDÉ AMÉLIORÉ DE SÉPARATION ET DE QUANTIFICATION D'ENZYMES PANCRÉATIQUES À L'AIDE DE CE-SDS
Applicants **
KASHIV BIOSCIENCES, LLC
Inventors
DHANANI, Chandrakant D
VASOYA, Kristal Kishorbhai
MAHAJAN, Mukesh
Priority Data
202421000983   05.01.2024   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3043
EPO Filing, Examination, Granting25237
Japan Filing, Examination, Granting2947
South Korea Filing, Examination, Granting3769
USA Filing, Examination, Granting10110
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Total: 45,106
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Abstract[English] The present disclosure relates to a method for improving separation and quantification profile of pancreatic protein mixture comprising at least one enzyme amylase, protease, and lipase, trypsin, chymotrypsin, elastase and kallikrein glandular and variant thereof through capillary electrophoresis Sodium dodecyl sulfate (CE-SDS). Furthermore, the invention provides a stable pancreatic protein sample comprising substantially free of digested protein which makes the pancreatic sample more suitable for analytical characterization.[French] La présente divulgation concerne un procédé d'amélioration du profil de séparation et de quantification du mélange de protéines pancréatiques comprenant au moins une enzyme amylase, protéase et lipase, trypsine, chymotrypsine, élastase et kallicréine glandulaire et variant de celle-ci, par électrophorèse capillaire sodium dodécyl sulfate (CE-SDS). En outre, l'invention concerne un échantillon de protéine pancréatique stable comprenant sensiblement exempt de protéine digérée qui rend l'échantillon pancréatique plus approprié pour une caractérisation analytique.

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