WO2026013449 - OXAZOLIDONE-DERIVED COMPOUNDS AND THEIR USE IN THE TREATMENT OF CHRONIC AND ACUTE PAIN

National phase entry is expected:
Publication Number WO/2026/013449
Publication Date 15.01.2026
International Application No. PCT/IB2025/000357
International Filing Date 11.07.2025
Title **
[English] OXAZOLIDONE-DERIVED COMPOUNDS AND THEIR USE IN THE TREATMENT OF CHRONIC AND ACUTE PAIN
[French] COMPOSÉS DÉRIVÉS D'OXAZOLIDONE ET LEUR UTILISATION DANS LE TRAITEMENT DE LA DOULEUR CHRONIQUE ET AIGUË
Applicants **
SEA4US - BIOTECNOLOGIA E RECURSOS MARINHOS, SA
Inventors
DOS SANTOS BALTAZAR DE LIMA, Pedro, Afonso
PINHEIRO COSTA BASTOS, André, Emanuel
FERREIRA DA SILVA MOURA, José, Eduardo
SZWARC DOS SANTOS, Beatriz
MAÇO ABREU, Ana, Rosa
CHEGÃO PISSARRA MONTEIRO, Ana, Alexandra
SEGÃO MONDRAGÃO, Miguel, Ângelo
PEREIRA, Ana Isabel, Pimenta, Gonçalves
ALHINHO BERNARDO, Ana, Fátima
TREMBLEAU, Laurent, Alain, Claude
VAN BERKOM., Leonardus, Wilhelmus, Adriaan
MATEUS AFONSO, Carlos, Alberto
MOREIRA, Rui, Ferreira, Alves
Priority Data
63/669,908   11.07.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3334
EPO Filing, Examination, Granting14411
Japan Filing, Examination, Granting2265
South Korea Filing, Examination, Granting2222
USA Filing, Examination, Granting6240
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Total: 28,472
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Abstract[English] currents expressed in the small diameter dorsal root neurons (sdDRGns). Such findings, together with those showing that oxazolidone and oxazolidone analogue compounds act as activity dependent blockers also lead to very reduced side-effects. The results disclosed herein show that oxazolidone and oxazolidone analogue compounds described herein are a viable alternative to the already existing pharmaceutical compounds used in the treatment of pain.[French] à tension activée exprimés dans les neurones à racines dorsales de petit diamètre (sdDRGn). De telles découvertes, conjointement avec celles révèlant que l'oxazolidone et les composés analogues d'oxazolidone agissent en tant que bloqueurs dépendant de l'activité, produisent également des effets secondaires très réduits. Les résultats divulgués révèlent que l'oxazolidone et les composés analogues d'oxazolidone présentés dans la divulgation sont une alternative viable aux composés pharmaceutiques déjà existants utilisés dans le traitement de la douleur.

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