WO2025141545 - CONTROLLER WITH PID LOGIC FOR SPECTROGRAM-BASED CONTROL OF BLOOD-BRAIN BARRIER OPENING
National phase entry is expected:
Publication Number
WO/2025/141545
Publication Date
03.07.2025
International Application No.
PCT/IB2024/063348
International Filing Date
31.12.2024
Title **
[English]
CONTROLLER WITH PID LOGIC FOR SPECTROGRAM-BASED CONTROL OF BLOOD-BRAIN BARRIER OPENING
[French]
DISPOSITIF DE COMMANDE À LOGIQUE PID POUR COMMANDE DE L'OUVERTURE DE LA BARRIÈRE HÉMATO-ENCÉPHALIQUE PAR SPECTROGRAMME
Applicants **
INSIGHTEC LTD.
Inventors
PLAKSIN, Michael
LEVY, Yoav
BAR-ZION, Avinoam
Priority Data
63/616,750
31.12.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Pages of Specification | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2084 | |
| EPO | Filing, Examination, Granting | 8460 | |
| Japan | Filing, Examination, Granting | 2171 | |
| South Korea | Filing, Examination, Granting | 2051 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
19,506
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Abstract[English]
A system for controllably changing a tissue property in a target volume. It comprises an ultrasound transducer that sonicates a target volume to change tissue properties by transmitting a sequence of acoustic pulses to the target volume, while a sensor array captures acoustic feedback generated by the sequence of acoustic pulses in the target volume. A controller (420) is provided, which (i) generates a spectrogram from the acoustic feedback, (ii) computationally calculates a degree of change of the tissue property in the target volume based on the spectrogram, and (iii) controls the ultrasound transducer based on the calculated degree of change of the tissue property to change the tissue property to a target degree set for a specific treatment.[French]
L'invention concerne un système pour modifier de manière contrôlée une propriété de tissu dans un volume cible. Le système comprend un transducteur ultrasonore qui crée une sonication dans un volume cible pour modifier des propriétés de tissu par transmission d'une séquence d'impulsions acoustiques au volume cible, tandis qu'un réseau de capteurs capture une retour acoustique généré par la séquence d'impulsions acoustiques dans le volume cible. Un dispositif de commande (420) est fourni, qui (i) génère un spectrogramme à partir du retour acoustique, (ii) calcule par ordinateur un degré de changement de la propriété du tissu dans le volume cible sur la base du spectrogramme, et (iii) commande le transducteur ultrasonore sur la base du degré de changement calculé de la propriété du tissu pour changer la propriété du tissu en un ensemble de degrés cible pour un traitement spécifique.