WO2025146618 - SYSTEMS AND METHODS FOR TREATING EXCESS PRESSURE HAVING AN ELASTIC MEMBRANE IN FLUID CONTACT WITH BODILY FLUID
National phase entry is expected:
Publication Number
WO/2025/146618
Publication Date
10.07.2025
International Application No.
PCT/IB2024/063324
International Filing Date
31.12.2024
Title **
[English]
SYSTEMS AND METHODS FOR TREATING EXCESS PRESSURE HAVING AN ELASTIC MEMBRANE IN FLUID CONTACT WITH BODILY FLUID
[French]
SYSTÈMES ET MÉTHODES DE TRAITEMENT D'UNE SURPRESSION COMPORTANT UNE MEMBRANE ÉLASTIQUE EN CONTACT FLUIDIQUE AVEC UN FLUIDE CORPOREL
Applicants **
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Inventors
STERGIOPULOS, Nikolaos
Priority Data
63/616,943
02.01.2024
US
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2631 | |
| EPO | Filing, Examination, Granting | 16484 | |
| Japan | Filing, Examination, Granting | 2650 | |
| South Korea | Filing, Examination, Granting | 2964 | |
| USA | Filing, Examination, Granting | 6740 |
Total:
31,469
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Abstract[English]
Systems and methods are provided for treating diseases that produce elevated pressure, e.g., intraocular pressure or cerebrospinal fluid pressure, such as glaucoma or hydrocephalus, wherein the device includes a housing shell, an elastic membrane, and a local constriction that reduces the area of the fluidic passageway through the housing shell and increases fluidic resistance of the flow of fluid through the passageway. At normal IOP levels, the elastic membrane engages the local constriction to prevent or reduce fluid flow across the passageway. When the average pressure between the inlet and outlet of the device varies, e.g., exceeds a predetermined threshold, the elastic membrane deforms and disengages the local constriction to thereby permit fluid flow across the passageway.[French]
L'invention concerne des systèmes et des méthodes pour traiter des maladies qui produisent une pression élevée, par exemple, une pression intraoculaire ou une pression de liquide céphalorachidien, telles que le glaucome ou l'hydrocéphalie, le dispositif comprenant une enveloppe de boîtier, une membrane élastique et un étranglement local qui réduit la surface du passage fluidique à travers l'enveloppe de boîtier et augmente la résistance fluidique de l'écoulement de fluide à travers le passage. Aux niveaux d'IOP normaux, la membrane élastique vient en prise avec l'étranglement local pour empêcher ou réduire l'écoulement de fluide à travers le passage. Lorsque la pression moyenne entre l'entrée et la sortie du dispositif varie, par exemple, dépasse un seuil prédéterminé, la membrane élastique se déforme et se sépare de l'étranglement local pour permettre ainsi l'écoulement de fluide à travers le passage.