WO2025141483 - METHOD FOR MODULATING AFUCOSYLATION LEVEL OF PERTUZUMAB

National phase entry is expected:
Publication Number WO/2025/141483
Publication Date 03.07.2025
International Application No. PCT/IB2024/063164
International Filing Date 25.12.2024
Title **
[English] METHOD FOR MODULATING AFUCOSYLATION LEVEL OF PERTUZUMAB
[French] PROCÉDÉ DE MODULATION DU NIVEAU DE DÉFUCOSYLATION DU PERTUZUMAB
Applicants **
INTAS PHARMACEUTICALS LTD.
Inventors
ADHIKARY, Laxmi
MAHALINGAM, Velu
SHAH, Kinchit
PATEL, Hiral S.
MISHRA, Surbhi
SINGH, Varsha
PALSOKAR, Mrunal
SETH, Mrinal
Priority Data
202321089627   29.12.2023   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1955
EPO Filing, Examination, Granting11624
Japan Filing, Examination, Granting1952
South Korea Filing, Examination, Granting1659
USA Filing, Examination, Granting5340
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Total: 22,530
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Abstract[English] cells/mL.[French] La présente invention concerne un procédé de modulation du niveau de défucosylation du pertuzumab, à l'aide d'un changement du pH de milieux de culture cellulaire, lorsque la culture cellulaire atteint le nombre de (18-22) x 106 cellules viables/mL.

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