WO2025120616 - METHOD AND DEVICE FOR MICROFLUIDIC FORMULATION OF STABLE NANOPARTICLES AS DRUG/BIOMOLECULES CARRIERS
National phase entry is expected:
Publication Number
WO/2025/120616
Publication Date
12.06.2025
International Application No.
PCT/IB2024/062698
International Filing Date
16.12.2024
Title **
[English]
METHOD AND DEVICE FOR MICROFLUIDIC FORMULATION OF STABLE NANOPARTICLES AS DRUG/BIOMOLECULES CARRIERS
[French]
PROCÉDÉ ET DISPOSITIF DE FORMULATION MICROFLUIDIQUE DE NANOPARTICULES STABLES EN TANT QUE SUPPORTS DE MÉDICAMENT/BIOMOLÉCULES
Applicants **
SHABANI, Shahrzad
Inventors
SHABANI, Shahrzad
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
IP India
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Natural Person
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1911 | |
| EPO | Filing, Examination, Granting | 8722 | |
| Japan | Filing, Examination, Granting | 2045 | |
| South Korea | Filing, Examination, Granting | 1762 | |
| USA | Filing, Examination, Granting | 9540 |
Total:
23,980
Contact Us
Abstract[English]
This invention involves a microfluidic chip used to create carrier nanoparticles for applications like cancer treatment and vaccine production. The chip is made of PDMS polymer and utilizes soft lithography techniques. The chip's design includes inlets for cationic water and oil phases, and an outlet with channels arranged perpendicular to each other to control nanoparticle size. The nanoparticles produced are 20-100 nm with a lipid coating which enhances cell absorption. They are also stable in vitro and in vivo, with a PDI index of 0. 07 indicating optimal uniformity and homogeneity.[French]
La présente invention concerne une puce microfluidique utilisée pour créer des nanoparticules de support pour des applications telles que le traitement du cancer et la production de vaccins. La puce est constituée de polymère PDMS et utilise des techniques de lithographie douce. La conception de la puce comprend des entrées pour des phases eau et huile cationiques, et une sortie avec des canaux disposés perpendiculairement les uns aux autres pour réguler la taille des nanoparticules. Les nanoparticules produites font de 20 à 100 nm avec un revêtement lipidique qui améliore l'absorption cellulaire. Elles sont également stables in vitro et in vivo, avec un indice de PDI de 0,07 indiquant une uniformité et une homogénéité optimales.