WO2025133872 - METHOD FOR REDUCING OXIDATION LEVELS IN VEDOLIZUMAB DURING CELL CULTURE PROCESS

National phase entry is expected:
Publication Number WO/2025/133872
Publication Date 26.06.2025
International Application No. PCT/IB2024/062690
International Filing Date 16.12.2024
Title **
[English] METHOD FOR REDUCING OXIDATION LEVELS IN VEDOLIZUMAB DURING CELL CULTURE PROCESS
[French] PROCÉDÉ DE RÉDUCTION DES NIVEAUX D'OXYDATION DANS LE VÉDOLIZUMAB PENDANT UN PROCESSUS DE CULTURE CELLULAIRE
Applicants **
INTAS PHARMACEUTICALS LTD.
Inventors
MAHALINGAM, Velu
SHAH, Kinchit
PATEL, Hiral S.
PANCHAXARI, Chitti
ADHIKARY, Laxmi
Priority Data
202321086787   19.12.2023   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1954
EPO Filing, Examination, Granting11587
Japan Filing, Examination, Granting1960
South Korea Filing, Examination, Granting1654
USA Filing, Examination, Granting4740
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Total: 21,895
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Abstract[English] The present invention provides a method of producing Vedolizumab, comprising supplementing cell culture with Methionine and thereby reducing the oxidation of cell culture.[French] La présente invention concerne un procédé de production de védolizumab, comprenant la supplémentation d'une culture cellulaire avec de la méthionine et ainsi la réduction de l'oxydation de la culture cellulaire.

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