WO2025126086 - SYSTEMS, DEVICES, AND METHODS FOR MICROFLUIDIC FLUID ANALYSIS

National phase entry is expected:
Publication Number WO/2025/126086
Publication Date 19.06.2025
International Application No. PCT/IB2024/062532
International Filing Date 11.12.2024
Title **
[English] SYSTEMS, DEVICES, AND METHODS FOR MICROFLUIDIC FLUID ANALYSIS
[French] SYSTÈMES, DISPOSITIFS ET PROCÉDÉS D'ANALYSE MICROFLUIDIQUE DE FLUIDES
Applicants **
AUFBAU MEDICAL INNOVATIONS LTD.
Inventors
HURLEY II, David D.
PENA, John T.G.
LEE, Hwi Yong
RAJAMANTHRILAGE, Apeksha C.
HO, Kathleen
BELDNER, Shayna F.
Priority Data
63/608,790   11.12.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3413
EPO Filing, Examination, Granting24417
Japan Filing, Examination, Granting3010
South Korea Filing, Examination, Granting3718
USA Filing, Examination, Granting9590
MasterCard Visa
Total: 44,148

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Described here are systems, devices, and methods useful for high-throughput and automated separation of extracellular matrix bodies using a microfluidic chip. A system for separating extra-cellular matrix bodies (ECMBs) from a biological fluid may comprise a holder configured to receive the biological fluid, a robot configured to transfer the biological fluid from the holder to a microfluidic chip, a chip connector configured to hold at least one microfluidic chip, a manifold coupled to the at least one microfluidic chip, and a negative pressure source coupled to the manifold. The negative pressure source may be configured to apply a negative pressure of between about 10 mm HG and about 760 mm HG to the at least one microfluidic chip.[French] L'invention concerne des systèmes, des dispositifs et des procédés utiles pour la séparation automatisée et à haut débit de corps de matrice extracellulaire à l'aide d'une puce microfluidique. Un système de séparation de corps de matrice extracellulaire d'un fluide biologique peut comprendre un support configuré pour recevoir le fluide biologique, un robot configuré pour transférer le fluide biologique du support à une puce microfluidique, un connecteur de puce configuré pour maintenir au moins une puce microfluidique, un collecteur raccordé à au moins une des puces microfluidiques, et une source de pression négative raccordée au collecteur. La source de pression négative peut être conçue pour appliquer une pression négative comprise entre environ 10 mm HG et environ 760 mm HG à ladite puce microfluidique.

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