WO2025099508 - ENHANCED ISOMALTULOSE PRODUCTION THROUGH RECOMBINANT HOST CELLS AND NUCLEIC ACID CONSTRUCTS ENCODING FUSION PROTEINS AND PROCESS THEREOF
National phase entry is expected:
Publication Number
WO/2025/099508
Publication Date
15.05.2025
International Application No.
PCT/IB2024/059737
International Filing Date
04.10.2024
Title **
[English]
ENHANCED ISOMALTULOSE PRODUCTION THROUGH RECOMBINANT HOST CELLS AND NUCLEIC ACID CONSTRUCTS ENCODING FUSION PROTEINS AND PROCESS THEREOF
[French]
PRODUCTION AMÉLIORÉE D'ISOMALTULOSE PAR L'INTERMÉDIAIRE DE CELLULES HÔTES RECOMBINÉES ET DE CONSTRUCTIONS D'ACIDE NUCLÉIQUE CODANT POUR DES PROTÉINES DE FUSION ET PROCÉDÉ ASSOCIÉ
Applicants **
SAINC ENERGY LIMITED
Inventors
THEVELEIN, Johan
SUBOTIĆ, Ana
VARGHESE, Saju
SOOD, Kamaljit S.
Priority Data
202311077096
11.11.2023
IN
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2892 | |
| EPO | Filing, Examination, Granting | 23829 | |
| Japan | Filing, Examination, Granting | 3145 | |
| South Korea | Filing, Examination, Granting | 3850 | |
| USA | Filing, Examination, Granting | 15140 |
Total:
48,856
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present subject matter relates generally to a recombinant host cell comprising a polynucleotide fragment encoding for a polypeptide fragment of a fusion protein. The present subject matter also relates to a polynucleotide fragment, a polypeptide fragment, an expression vector and an expression vector replicating cell used for the production and development of the recombinant host cell. Further, the present subject matter relates to a process for production of isomaltulose from sucrose using the recombinant host cell. The present subject matter also pertains to an isomaltulose obtained from the process. The recombinant host cell expresses a cell-wall anchored sucrose isomerase enzyme, resulting in an improved conversion of sucrose to isomaltulose.[French]
La présente invention concerne d'une manière générale une cellule hôte recombinante comprenant un fragment polynucléotidique codant pour un fragment polypeptidique d'une protéine de fusion. La présente invention concerne également un fragment polynucléotidique, un fragment polypeptidique, un vecteur d'expression et une cellule de réplication de vecteur d'expression utilisés pour la production et le développement de la cellule hôte recombinante. En outre, la présente invention concerne un procédé de production d'isomaltulose à partir de saccharose à l'aide de la cellule hôte recombinante. La présente invention concerne également un isomaltulose obtenu à partir dudit procédé. La cellule hôte recombinante exprime une enzyme de saccharose isomérase ancrée à une paroi cellulaire, ce qui permet d'obtenir une conversion améliorée du saccharose en isomaltulose.