WO2025068943 - KAT6 INHIBITORS

National phase entry is expected:
Publication Number WO/2025/068943
Publication Date 03.04.2025
International Application No. PCT/IB2024/059418
International Filing Date 26.09.2024
Title **
[English] KAT6 INHIBITORS
[French] INHIBITEURS DE KAT6
Applicants **
BEONE MEDICINES I GMBH
BEONE PHARMACEUTICAL (SUZHOU) CO., LTD.
Inventors
WANG, Qiuwen
WANG, Yayi
GUO, Yunhang
QIN, Ling
WANG, Yuxi
WANG, Zhiwei
Priority Data
PCT/CN2024/096981   03.06.2024   CN
PCT/CN2023/122071   27.09.2023   CN
PCT/CN2024/074987   31.01.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting5787
EPO Filing, Examination, Granting28116
Japan Filing, Examination, Granting2763
South Korea Filing, Examination, Granting3301
USA Filing, Examination, Granting11440
MasterCard Visa
Total: 51,407

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Disclosed herein are compounds used as inhibitors of KAT6, or a pharmaceutically acceptable salt, deuterated analog, N-oxide, or tautomer thereof. Also disclosed is a pharmaceutical composition comprising a compound disclosed herein, and a method for treating or preventing a disorder or a disease responsive to the inhibition of KAT6 activity in a subject using the same. In some embodiments, the compounds are of formula (I), wherein values for the variables are disclosed herein.[French] L'invention concerne des composés utilisés en tant qu'inhibiteurs de KAT6, ou un sel pharmaceutiquement acceptable, un analogue deutéré, un N-oxyde ou un tautomère de ceux-ci. L'invention concerne également une composition pharmaceutique comprenant un composé de l'invention, et une méthode de traitement ou de prévention d'un trouble ou d'une maladie en réponse à l'inhibition de l'activité de KAT6 chez un sujet l'utilisant. Dans certains modes de réalisation, les composés sont de formule (I), des valeurs pour les variables étant divulguées dans la description.

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