WO2025008781 - METHOD OF PURIFICATION

National phase entry:
Publication Number WO/2025/008781
Publication Date 09.01.2025
International Application No. PCT/IB2024/056536
International Filing Date 04.07.2024
Title **
[English] METHOD OF PURIFICATION
[French] PROCÉDÉ DE PURIFICATION
Applicants **
CSL BEHRING AG
Inventors
DOLLINGER, Peter
HEERING, Dorota
PAL CHOWDHURY, Nilanjan
PILZ, Tessa
Priority Data
23183376.5   04.07.2023   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3119
EPO Filing, Examination, Granting12706
Japan Filing, Examination, Granting2198
South Korea Filing, Examination, Granting2035
USA Filing, Examination, Granting5640
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Total: 25,698

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure relates to methods of isolating a protein-of-interest enriched solution, such as an immunoglobulin G (IgG), and a plurality of protein-of-interest depleted fractions from a protein mixture, such as plasma or a fraction thereof, using continuous chromatography. The present disclosure also relates to a continuous chromatography system for separating a protein-of-interest from a protein mixture, formulations and uses of the purified products thereof.[French] La présente invention concerne des procédés d'isolement d'une solution enrichie en protéines d'intérêt, telle qu'une immunoglobuline G (IgG), et d'une pluralité de fractions appauvries en protéines d'intérêt à partir d'un mélange de protéines, tel qu'un plasma ou une fraction de celui-ci, à l'aide d'une chromatographie continue. La présente invention concerne également un système de chromatographie continue pour séparer une protéine d'intérêt d'un mélange de protéines, des formulations et des utilisations des produits purifiés de celui-ci.

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