WO2024257023 - TYK2 PSEUDOKINASE LIGANDS AND USES THEREOF

National phase entry is expected:
Publication Number WO/2024/257023
Publication Date 19.12.2024
International Application No. PCT/IB2024/055815
International Filing Date 14.06.2024
Title **
[English] TYK2 PSEUDOKINASE LIGANDS AND USES THEREOF
[French] LIGANDS DE PSEUDOKINASE TYK2 ET LEURS UTILISATIONS
Applicants **
ALEMBIC PHARMACEUTICALS LIMITED
Inventors
KURHADE, Suresh
PRIYADARSHANI, Garima
SISODIYA, Shailendra
HALLE, Mahesh
KAPURE, Jeevak Sopanrao
KURIAPPAN, Jissy Akkarapattiakal
MALLIK, Sanchari Basu
TANDON, Amol
SUBRAMANIAM, Ganesan
IYER, Abishek Venkatasubramanian
Priority Data
202321040658   14.06.2023   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting5925
EPO Filing, Examination, Granting107145
Japan Filing, Examination, Granting4894
South Korea Filing, Examination, Granting7819
USA Filing, Examination, Granting26040
MasterCard Visa
Total: 151,823

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Described herein are compounds of formula (A) that are useful in the modulation of inflammation and treating associated disorders by acting on TYK2 to cause TYK2-mediated signal transduction inhibition. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, an endocrine disorder, a neurological disorder, a proliferative disorder, or a disorder associated with transplantation.[French] L'invention concerne des composés de formule A qui sont utiles dans la modulation de l'inflammation et le traitement de troubles associés par action sur TYK2 pour provoquer une inhibition de la transduction de signal médiée par TYK2. Dans certains modes de réalisation, le trouble médié par TYK2 est un trouble auto-immun, un trouble inflammatoire, un trouble endocrinien, un trouble neurologique, un trouble prolifératif ou un trouble associé à une transplantation.

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