WO2024246838 - COMPOUNDS FOR THE DEGRADATION OF EGFR KINASE

National phase entry is expected:
Publication Number WO/2024/246838
Publication Date 05.12.2024
International Application No. PCT/IB2024/055315
International Filing Date 30.05.2024
Title **
[English] COMPOUNDS FOR THE DEGRADATION OF EGFR KINASE
[French] COMPOSÉS POUR LA DÉGRADATION DE LA KINASE EGFR
Applicants **
BEONE MEDICINES I GMBH
BEONE PHARMACEUTICAL (SUZHOU) CO., LTD.
Inventors
LEI, Bailin
ZHAO, Yizhou
QI, Xinzhu
LIU, Guanjun
WANG, Zhiwei
LIU, Huaqing
Priority Data
PCT/CN2023/097387   31.05.2023   CN
PCT/CN2023/125498   19.10.2023   CN
PCT/CN2024/090756   30.04.2024   CN
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting6080
EPO Filing, Examination, Granting74672
Japan Filing, Examination, Granting4252
South Korea Filing, Examination, Granting6251
USA Filing, Examination, Granting21340
MasterCard Visa
Total: 112,595

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Disclosed herein are novel bifunctional compounds formed by conjugating EGFR inhibitor moieties with E3 ligase ligand moieties, methods of preparation, and uses thereof.[French] L'invention concerne de nouveaux composés bifonctionnels formés par conjugaison de fractions d'inhibiteur d'EGFR avec des fractions de ligand de ligase E3, des procédés de préparation et des utilisations de ceux-ci.

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