WO2024218752 - PHARMACEUTICAL COMPOSITION FOR VACCINATION AGAINST CYTOMEGALOVIRUS INFECTIONS

National phase entry:
Publication Number WO/2024/218752
Publication Date 24.10.2024
International Application No. PCT/IB2024/053866
International Filing Date 20.04.2024
Title **
[English] PHARMACEUTICAL COMPOSITION FOR VACCINATION AGAINST CYTOMEGALOVIRUS INFECTIONS
[French] COMPOSITION PHARMACEUTIQUE POUR LA VACCINATION CONTRE LES INFECTIONS À CYTOMÉGALOVIRUS
Applicants **
INSTAR TECHNOLOGIES A.S.
Inventors
STRÁNSKÁ, Denisa
BOŠTIK, Pavel
SAGAR, Gyan
JANOVSKÁ, Sylva
ŠLEHA, Radek
Priority Data
PV2023-162   21.04.2023   CZ
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3185
EPO Filing, Examination, Granting25424
Japan Filing, Examination, Granting3165
South Korea Filing, Examination, Granting4051
USA Filing, Examination, Granting11940
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Total: 47,765

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Abstract[English] The present invention relates to the field of prevention of herpes infections, in particularly to a pharmaceutical composition for oromucosal administration for vaccination against cytomegalovirus infections and the use of cytomegalovirus glycoprotein B. The pharmaceutical composition comprises, as an active ingredient, cytomegalovirus glycoprotein B, which is releasably contained in the pharmaceutical composition in a carrier for oromucosal administration of physiologically active agents, comprising at least one flexible active layer of polymeric nanofibers in which cytomegalovirus glycoprotein B is releasably contained, and at least one cover layer of polymeric nanofibers.[French] La présente invention relève du domaine de la prévention des infections à herpès, et concerne en particulier une composition pharmaceutique pour administration oromucosale prévue pour la vaccination contre les infections à cytomégalovirus et l'utilisation de la glycoprotéine B de cytomégalovirus. La composition pharmaceutique contient, en tant que principe actif, une glycoprotéine B de cytomégalovirus, qui est contenue de manière libérable dans la composition pharmaceutique dans un support prévu pour l'administration oromucosale d'agents physiologiquement actifs, comprenant au moins une couche active flexible de nanofibres polymères qui contient de manière libérable la glycoprotéine B de cytomégalovirus, et au moins une couche de couverture en nanofibres polymères.

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