WO2024218743 - MULTI-FUNCTIONAL MOLECULES COMPRISING GLYCANS AND USES THEREOF
National phase entry is expected:
Publication Number
WO/2024/218743
Publication Date
24.10.2024
International Application No.
PCT/IB2024/053854
International Filing Date
19.04.2024
Title **
[English]
MULTI-FUNCTIONAL MOLECULES COMPRISING GLYCANS AND USES THEREOF
[French]
MOLÉCULES MULTIFONCTIONNELLES COMPRENANT DES GLYCANES ET LEURS UTILISATIONS
Applicants **
GLYCOERA AG
Inventors
GANGULY, Tanmoy
KAUNDINYA, Ganesh
BACK, Jonathan Albert
COTTER, Kellie
MALLY, Manuela
MANNI, Michela
ZBINDEN, Reto
Priority Data
63/497,567
21.04.2023
US
63/505,844
02.06.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 4129 | |
| EPO | Filing, Examination, Granting | 40676 | |
| Japan | Filing, Examination, Granting | 3543 | |
| South Korea | Filing, Examination, Granting | 4800 | |
| USA | Filing, Examination, Granting | 18990 |
Total:
72,138
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
Provided herein are multi-functional molecules comprising: (1) a first moiety that binds to an endocytic receptor; and (2) a second moiety that binds to a target; and optionally, (3) a third moiety that binds to an endocytic receptor. In some embodiments, a first moiety binds to a target under a first set of conditions and/or a second set of conditions. In some embodiments, a second moiety binds to a target under a first set of conditions. In some embodiments, a third moiety binds to an endocytic receptor under a second set of conditions. Further provided herein are compositions comprising multi-functional molecules disclosed herein and/or nucleic acids encoding the same, as well as methods of making and using the same.[French]
L'invention concerne des molécules multifonctionnelles comprenant : (1) une première fraction qui se lie à un récepteur endocytique ; et (2) une deuxième fraction qui se lie à une cible ; et éventuellement, (3) une troisième fraction qui se lie à un récepteur endocytique. Dans certains modes de réalisation, une première fraction se lie à une cible dans un premier ensemble de conditions et/ou un deuxième ensemble de conditions. Dans certains modes de réalisation, une deuxième fraction se lie à une cible dans un premier ensemble de conditions. Dans certains modes de réalisation, une troisième fraction se lie à un récepteur endocytique dans un deuxième ensemble de conditions. L'invention concerne en outre des compositions comprenant des polypeptides glycomodifiés et/ou des acides nucléiques codant ceux-ci, ainsi que leurs procédés de fabrication et d'utilisation.