WO2024214044 - MULTICOMPONENT COMPLEXES, INCLUDING SALTS AND HYDRATES AND SOLVATES, OF INUPADENANT

National phase entry is expected:
Publication Number WO/2024/214044
Publication Date 17.10.2024
International Application No. PCT/IB2024/053562
International Filing Date 11.04.2024
Title **
[English] MULTICOMPONENT COMPLEXES, INCLUDING SALTS AND HYDRATES AND SOLVATES, OF INUPADENANT
[French] COMPLEXES MULTICOMPOSANTS COMPRENANT DES SELS, DES HYDRATES ET DES SOLVATES D'INUPADENANT
Applicants **
ITEOS BELGIUM SA
Inventors
REECE, Hayley Ann
BOULTON, Katharine
VAN BERKEL, Chantalle
ARET, Edwin
ROSS, Sally
GANGOLLI, Esha
SRIVASTAVA, Shouraydeep
LAGER, Joanne
MADASAMY, Pratheepan
ROSSETTI, Maura
MARTINOLI, Chiara
NAP, Wilhelmina
Priority Data
63/458,761   12.04.2023   US
63/458,840   12.04.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting14905
EPO Filing, Examination, Granting395876
Japan Filing, Examination, Granting6181
South Korea Filing, Examination, Granting19775
USA Filing, Examination, Granting110740
MasterCard Visa
Total: 547,477

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure relates to multicomponent complexes, such as salt forms of inupadenant, and hydrates and solvates thereof, formed by the combination of inupadenant and a coformer, such as an acid. In some embodiments, the present disclosure relates to crystalline and amorphous salts of inupadenant, and hydrates and solvates thereof. In some embodiments, the present disclosure relates to pharmaceutically acceptable salts of inupadenant, and hydrates and solvates thereof. In some embodiments, the present disclosure relates to inorganic salts of inupadenant, and hydrates and solvates thereof. In some embodiments, the present disclosure relates to organic salts of inupadenant, and hydrates and solvates thereof. In some embodiments, the present disclosure relates to compositions, dosage forms, kits, methods, and uses relating to multicomponent complexes of inupadenant, and hydrates and solvates thereof.[French] La présente divulgation concerne des complexes multicomposants, tels que des formes salines d'inupadenant, et des hydrates et des solvates de ceux-ci, formés par la combinaison d'inupadenant et d'un co-formeur, tel qu'un acide. Dans certains modes de réalisation, la présente divulgation concerne des sels cristallins et amorphes d'inupadenant, et des hydrates et des solvates de ceux-ci. Dans certains modes de réalisation, la présente divulgation concerne des sels pharmaceutiquement acceptables d'inupadenant, et des hydrates et des solvates de ceux-ci. Dans certains modes de réalisation, la présente divulgation concerne des sels inorganiques d'inupadenant, et des hydrates et des solvates de ceux-ci. Dans certains modes de réalisation, la présente divulgation concerne des sels organiques d'inupadenant, et des hydrates et des solvates de ceux-ci. Dans certains modes de réalisation, la présente divulgation concerne des compositions, des formes posologiques, des kits, des procédés et des utilisations se rapportant à des complexes multicomposants d'inupadenant, et des hydrates et des solvates de ceux-ci.

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