WO2024201423 - MICROTUBULE-ASSOCIATED PROTEIN TAU TARGETING SIRNAS AND USES THEREOF

National phase entry is expected:
Publication Number WO/2024/201423
Publication Date 03.10.2024
International Application No. PCT/IB2024/053120
International Filing Date 29.03.2024
Title **
[English] MICROTUBULE-ASSOCIATED PROTEIN TAU TARGETING SIRNAS AND USES THEREOF
[French] ARNSI CIBLANT LA PROTÉINE TAU ASSOCIÉE AUX MICROTUBULES ET LEURS UTILISATIONS
Applicants **
BIORCHESTRA CO., LTD.
Inventors
RYU, Jin-Hyeob
PARK, Young Jin
PARK, Suhyeong
LIM, Yu Na
KIM, Insun
KWON, Mincheol
KIM, Jihye
Priority Data
63/493,244   30.03.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting6599
EPO Filing, Examination, Granting143101
Japan Filing, Examination, Granting5020
South Korea Filing, Examination, Granting6356
USA Filing, Examination, Granting58240
MasterCard Visa
Total: 219,316

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure relates to siRNA, which target MAPT transcript in a cell, leading to reduced expression of MAPT protein. Reduction of MAPT protein expression is beneficial for the treatment of certain medical disorders, e.g., a tauopathy.[French] La présente invention concerne un ARNsi qui cible un transcrit MAPT dans une cellule, conduisant à une expression réduite de la protéine MAPT. La réduction de l'expression de la protéine MAPT est bénéfique pour le traitement de certains troubles médicaux, par exemple, une tauopathie.

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