WO2024176152 - USE OF ANTI-FAM19A5 ANTAGONISTS FOR TREATING HEARING DISORDERS

National phase entry:
Publication Number WO/2024/176152
Publication Date 29.08.2024
International Application No. PCT/IB2024/051688
International Filing Date 21.02.2024
Title **
[English] USE OF ANTI-FAM19A5 ANTAGONISTS FOR TREATING HEARING DISORDERS
[French] UTILISATION D'ANTAGONISTES ANTI-FAM19A5 POUR LE TRAITEMENT DE TROUBLES AUDITIFS
Applicants **
NEURACLE SCIENCE CO., LTD.
Inventors
SEONG, Jae Young
PARK, Yosub
BOK, Jinwoong
MIN, Hyehyun
KIM, Han Byul
Priority Data
63/486,187   21.02.2023   US
63/595,942   03.11.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting5208
EPO Filing, Examination, Granting75629
Japan Filing, Examination, Granting4266
South Korea Filing, Examination, Granting4468
USA Filing, Examination, Granting20640
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Total: 110,211

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Abstract[English] The present disclosure relates to the use of FAM19A5 antagonists (e.g., anti-FAM19A5 antibody or LRRC4 family mimic molecules) to treat a wide range of hearing disorders. The present disclosure also provides methods of using such antagonists to enhance one or more properties of ribbon synapses.[French] La présente divulgation concerne l'utilisation d'antagonistes de FAM19A5 (par exemple, un anticorps anti-FAM19A5 ou des molécules mimétiques de la famille LRRC4) pour traiter une large gamme de troubles auditifs. La présente divulgation concerne également des procédés d'utilisation de tels antagonistes pour améliorer une ou plusieurs propriétés de synapses en ruban.

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