WO2025120373 - METHODS OF DETERMINING POTENCY OF A HUMAN NEONATAL FC RECEPTOR ANTAGONIST

National phase entry is expected:
Publication Number WO/2025/120373
Publication Date 12.06.2025
International Application No. PCT/IB2024/000716
International Filing Date 04.12.2024
Title **
[English] METHODS OF DETERMINING POTENCY OF A HUMAN NEONATAL FC RECEPTOR ANTAGONIST
[French] PROCÉDÉS DE DÉTERMINATION DE LA PUISSANCE D'UN ANTAGONISTE DU RÉCEPTEUR FC NÉONATAL HUMAIN
Applicants **
ARGENX BV
Inventors
BORGIONS, Filip
HANSSENS, Valerie
Priority Data
2318512.7   04.12.2023   GB
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3329
EPO Filing, Examination, Granting32015
Japan Filing, Examination, Granting3391
South Korea Filing, Examination, Granting4461
USA Filing, Examination, Granting12140
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Total: 55,336

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Methods of determining the potency of a human neonatal Fc receptor (FcRn) antagonist composition in inhibiting the binding of human IgG to FcRn using a competition binding assay are provided. Kits for carrying out said methods, and methods of manufacturing a FcRn antagonist composition comprising said methods of determining potency are also provided.[French] Sont divulgués des procédés de détermination de la puissance d'une composition antagoniste du récepteur Fc néonatal humain (FcRn) à inhiber la liaison d'une IgG humaine à FcRn à l'aide d'un essai de liaison par compétition. Des kits pour mettre en œuvre lesdits procédés, et des procédés de fabrication d'une composition antagoniste de FcRn comprenant lesdits procédés de détermination de puissance sont aussi divulgués.

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