WO2025109372 - COMPOSITION AND METHOD FOR REDUCING RISK OF HYPOCALCEMIA IN PERIPARTURIENT RUMINANT ANIMALS

National phase entry is expected:
Publication Number WO/2025/109372
Publication Date 30.05.2025
International Application No. PCT/IB2024/000663
International Filing Date 20.11.2024
Title **
[English] COMPOSITION AND METHOD FOR REDUCING RISK OF HYPOCALCEMIA IN PERIPARTURIENT RUMINANT ANIMALS
[French] COMPOSITION ET PROCÉDÉ POUR RÉDUIRE LE RISQUE D'HYPOCALCÉMIE CHEZ DES ANIMAUX RUMINANTS PÉRI-PARTURIENTS
Applicants **
PROTEKTA INC.
Inventors
JAKOBSEN, Morten
JAKOBSEN, Lasse
MARTIN, Rod
CONNELLY, Meghan
HOFFMAN, Patrick
Priority Data
18/830,440   10.09.2024   US
18/618,702   27.03.2024   US
63/601,401   21.11.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2527
EPO Filing, Examination, Granting17275
Japan Filing, Examination, Granting2514
South Korea Filing, Examination, Granting2908
USA Filing, Examination, Granting6540
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Total: 31,764

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] A first method of reducing risk of periparturient hypocalcemia in a periparturient ruminant animal involves: measuring blood phosphorus concentration in the animal; and, administering a composition containing a phosphorus-binding compound and optionally, a pharmacologically acceptable carrier to the animal during at least part of a prepartum period of the animal. A second method of reducing risk of periparturient hypocalcemia in a periparturient ruminant animal involves: measuring an aluminum concentration in a feed composition; and, administering a composition containing a phosphorus-binding compound and optionally, a pharmacologically acceptable carrier to the animal during at least part of a prepartum period of the animal. In both methods, the composition having an effective amount of the phosphorus-binding compound to control the blood phosphorus concentration in a range of 1.5-3.5 mg P per dL of blood in the animal.[French] Un premier procédé de réduction du risque d'hypocalcémie péri-parturiente chez un animal ruminant péri-parturient consiste à : mesurer la concentration de phosphore sanguin chez l'animal ; et, administrer une composition contenant un composé de liaison au phosphore et éventuellement, un support pharmacologiquement acceptable à l'animal pendant au moins une partie d'une période pré-partum de l'animal. Un second procédé de réduction du risque d'hypocalcémie péri-parturiente chez un animal ruminant péri-parturient consiste à : mesurer une concentration d'aluminium dans une composition d'alimentation ; et, administrer une composition contenant un composé de liaison au phosphore et éventuellement, un support pharmacologiquement acceptable à l'animal pendant au moins une partie d'une période pré-partum de l'animal. Dans les deux procédés, la composition présente une quantité efficace du composé de liaison au phosphore afin de réguler la concentration en phosphore sanguin dans une plage de 1,5 à 3,5 mg P par dL de sang chez l'animal.

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