WO2024261531 - COMPOSITIONS AND METHODS TO MODULATE TUMOR MICROENVIRONMENT ASSOCIATED LONG NONCODING RNAS

National phase entry:
Publication Number WO/2024/261531
Publication Date 26.12.2024
International Application No. PCT/IB2024/000333
International Filing Date 21.06.2024
Title **
[English] COMPOSITIONS AND METHODS TO MODULATE TUMOR MICROENVIRONMENT ASSOCIATED LONG NONCODING RNAS
[French] COMPOSITIONS ET MÉTHODES POUR MODULER DES ARN LONGS NON CODANTS ASSOCIÉS À UN MICROENVIRONNEMENT TUMORAL
Applicants **
HAYA THERAPEUTICS SA
Inventors
OUNZAIN, Samir
MOLLER TORDENMALM, Emely
BLESSING, Daniel, Roman
Priority Data
63/523,001   23.06.2023   US
63/587,332   02.10.2023   US
63/651,270   23.05.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4813
EPO Filing, Examination, Granting30131
Japan Filing, Examination, Granting3071
South Korea Filing, Examination, Granting3905
USA Filing, Examination, Granting14340
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Total: 56,260

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Abstract[English] Disclosed herein are modulators of a long non-coding RNA (IncRNA), wherein an expression of the IncRNA is associated with an activation of a cancer-associated fibroblast (CAP). Further provided herein are methods of inhibiting a growth of a solid tumor or facilitating access to a solid tumor in a subject in need thereof.[French] La divulgation concerne des modulateurs d'un long ARN non codant (ARNInc), une expression de l'ARNInc étant associée à l'activation d'un fibroblaste associé au cancer (CAP). La divulgation concerne en outre des méthodes d'inhibition de la croissance d'une tumeur solide ou de facilitation de l'accès à une tumeur solide chez un sujet en ayant besoin.

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