WO2024134361 - SALT ACTIVATABLE DISSOLVABLE POLYMERIC EYE INSERTS AND KIT OF THE SAME

National phase entry is expected:
Publication Number WO/2024/134361
Publication Date 27.06.2024
International Application No. PCT/IB2023/062546
International Filing Date 12.12.2023
Title **
[English] SALT ACTIVATABLE DISSOLVABLE POLYMERIC EYE INSERTS AND KIT OF THE SAME
[French] INSERTS OCULAIRES POLYMÈRES SOLUBLES ACTIVABLES PAR UN SEL ET KIT DE CEUX-CI
Applicants **
ALCON INC.
Inventors
REBOUL, Adam C.
RAMIREZ, Katily
HONG, Ye
LU, Qiaozhi
Priority Data
63/477,109   23.12.2022   US
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Translation

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2142
EPO Filing, Examination, Granting10285
Japan Filing, Examination, Granting2324
South Korea Filing, Examination, Granting2243
USA Filing, Examination, Granting4740
MasterCard Visa
Total: 21,734

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Polymeric eye inserts are provided that may be dissolvable when placed in the cul-de-sac of the eye. These inserts may contain one or more mucoadhesive polymers, a sodium alginate as well as at least one humectant so that, when inserted into the eye, they may absorb tears, and dissolve and slowly release lubricant into the tear film to lubricate and protect the ocular surface for an extended duration of time. The sodium alginate containing eye insert may vary dissolution time on the ocular surface for a longer lasting relief, may reduce dosing frequency and patient burden typically associated with topical drop usage. These polymeric eye inserts also may include one or more pharmaceutically active agents.[French] La présente invention concerne des inserts oculaires polymères qui peuvent être solubles lorsqu'ils sont placés dans le cul-de-sac de l'œil. Ces inserts peuvent contenir un ou plusieurs polymères mucoadhésifs, un alginate de sodium ainsi qu'au moins un humectant de sorte que, lorsqu'ils sont insérés dans l'œil, ils peuvent absorber les larmes, et dissoudre et libérer lentement un lubrifiant dans le film lacrymal pour lubrifier et protéger la surface oculaire pendant une durée prolongée. L'insert oculaire contenant de l'alginate de sodium peut faire varier le temps de dissolution sur la surface oculaire pour un soulagement durable, peut réduire la fréquence de dosage et la charge sur le patient généralement associée à un usage local des gouttes. Ces inserts oculaires polymères peuvent également comprendre un ou plusieurs agents de qualité pharmaceutique.

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