WO2025114753 - SCAFFOLD FOR CORNEAL REGENERATION AND METHOD FOR PRODUCING THE SAME
National phase entry is expected:
Publication Number
WO/2025/114753
Publication Date
05.06.2025
International Application No.
PCT/IB2023/062042
International Filing Date
30.11.2023
Title **
[English]
SCAFFOLD FOR CORNEAL REGENERATION AND METHOD FOR PRODUCING THE SAME
[French]
ÉCHAFAUDAGE DESTINÉ À LA RÉGÉNÉRATION CORNÉENNE ET SA MÉTHODE DE PRODUCTION
Applicants **
MEDEZE TREASURY PTE. LTD
Inventors
KHEMARANGSAN, Veerapol
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2423 | |
| EPO | Filing, Examination, Granting | 12129 | |
| Japan | Filing, Examination, Granting | 2358 | |
| South Korea | Filing, Examination, Granting | 2241 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
23,891
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Abstract[English]
Disclosed is a scaffold for corneal regeneration and a method to produce thereof. The scaffold includes at least one layer of aligned fibers. The aligned fibers include a biocompatible polycaprolactone (PCL) and a collagen. The PCL and collagen have a mass ratio in the range of 77:23 to 42:58. Each layer of the aligned fibers has a thickness that is preferably from 15 to 20 μm. The scaffold has various properties that include but are not limited to a visible light transmittance in the range of 50 to 95%; a tensile strength less than or equal to 19.1 MPa; and an elasticity modulus in the range of 1 MPa to 34 MPa.[French]
L'invention divulgue un échafaudage destiné à la régénération cornéenne et une méthode de production associée. L'échafaudage comprend au moins une couche de fibres alignées. Les fibres alignées comprennent une polycaprolactone (PCL) biocompatible et un collagène. Le PCL et le collagène ont un rapport massique dans la plage de 77:23 à 42:58. Chaque couche des fibres alignées a une épaisseur qui est de préférence de 15 à 20 µm. L'échafaudage a diverses propriétés qui comprennent, entre autres, une transmittance en lumière visible dans la plage de 50 à 95 %, une résistance à la traction inférieure ou égale à 19,1 MPa, et un module d'élasticité dans la plage de 1 MPa à 34 MPa.