WO2024110863 - PROCESS AND INTERMEDIATES FOR PREPARING ((1R,2S,4R)-4-((5-(4-((R)-7-CHLORO-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)-5-METHYLTHIOPHENE-2-CARBONYL)PYRIMIDIN-4-YL)AMINO)-2-HYDROXYCYCLOPENTYL)METHYL SULFAMATE
National phase entry is expected:
Publication Number
WO/2024/110863
Publication Date
30.05.2024
International Application No.
PCT/IB2023/061737
International Filing Date
21.11.2023
Title **
[English]
PROCESS AND INTERMEDIATES FOR PREPARING ((1R,2S,4R)-4-((5-(4-((R)-7-CHLORO-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL)-5-METHYLTHIOPHENE-2-CARBONYL)PYRIMIDIN-4-YL)AMINO)-2-HYDROXYCYCLOPENTYL)METHYL SULFAMATE
[French]
PROCÉDÉ ET INTERMÉDIAIRES POUR LA PRÉPARATION DE SULFAMATE DE ((1R,2S,4R)-4-((5-(4-((R)-7-CHLORO-1,2,3,4-TÉTRAHYDROISOQUINOLIN-1-YL)-5-MÉTHYLTHIOPHÈNE-2-CARBONYL) PYRIMIDIN-4-YL) AMINO)-2-HYDROXYCYCLOPENTYL) MÉTHYLE
Applicants **
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventors
BAILEY, John Daniel
WAETZIG, Joshua David
TRUONG, Jonathan Vinh-Phu
Priority Data
63/384,657
22.11.2022
US
63/509,952
23.06.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2336 | |
| EPO | Filing, Examination, Granting | 11961 | |
| Japan | Filing, Examination, Granting | 2394 | |
| South Korea | Filing, Examination, Granting | 2517 | |
| USA | Filing, Examination, Granting | 5140 |
Total:
24,348
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present disclosure relates to a process for preparing ((1R,2S,4R)-4-((5-(4-((R)-7- chloro-1,2,3,4-tetrahydroisoquinolin-1-yl)-5-methylthiophene-2-carbonyl)pyrimidin-4- yl)amino)-2-hydroxycyclopentyl)methyl sulfamate and to novel intermediates used in the process.[French]
La présente invention concerne un procédé de préparation de sulfamate de ((1R,2S,4R)-4-((5-(4-((R)-7-chloro-1,2,3,4-tétrahydroisoquinolin-1-yl)-5-méthylthiophène-2-carbonyl) pyrimidin-4-yl) amino)-2-hydroxycyclopentyl) méthyle et de nouveaux intermédiaires utilisés dans le procédé.