WO2024110803 - POLYMERIC COMPOUNDS COMPRISING ANTINEOPLASTIC AGENTS
National phase entry:
Publication Number
WO/2024/110803
Publication Date
30.05.2024
International Application No.
PCT/IB2023/061127
International Filing Date
03.11.2023
Title **
[English]
POLYMERIC COMPOUNDS COMPRISING ANTINEOPLASTIC AGENTS
[French]
COMPOSÉS POLYMÈRES COMPRENANT DES AGENTS ANTINÉOPLASIQUES
Applicants **
SONY GROUP CORPORATION
Inventors
MATRAY, Tracy
VANBRUNT, Michael
MCCUTCHEON, John Michael
Priority Data
63/384,712
22.11.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Pages of Specification | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 4249 | |
| EPO | Filing, Examination, Granting | 56743 | |
| Japan | Filing, Examination, Granting | 3995 | |
| South Korea | Filing, Examination, Granting | 5386 | |
| USA | Filing, Examination, Granting | 17990 |
Total:
88,363
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
A water soluble polymeric compound is disclosed. The compound comprises: i) one or more antineoplastic agents; ii) a heteroalkylene backbone comprising negatively charged groups at physiological pH; iii) one or more linear or branched linkers comprising a self-immolative group and an optional spacer group, the linker linking each antineoplastic agent to the heteroalkylene backbone; and iv) a reactive group capable of forming a covalent bond to a targeting moiety. The water soluble polymeric compound finds utility in a number of applications, including use as therapeutic agents for various treatment methods.[French]
Un composé polymère soluble dans l'eau est divulgué. Le composé comprend : i) un ou plusieurs agents antinéoplasiques ; ii) un squelette hétéroalkylène comprenant des groupes chargés négativement à un pH physiologique ; iii) un ou plusieurs lieurs linéaires ou ramifiés comprenant un groupe auto-immolable et un groupe espaceur facultatif, le lieur liant chaque agent antinéoplasique au squelette hétéroalkylène ; et iv) un groupe réactif permettant de former une liaison covalente à une fraction de ciblage. Le composé polymère soluble dans l'eau trouve une utilité dans un certain nombre d'applications, comprenant l'utilisation en tant qu'agents thérapeutiques pour divers procédés de traitement.