WO2024018350 - TREATMENT OF AIHA WITH BAFF OR BAFF RECEPTOR INHIBITORY ANTIBODIES

National phase entry:
Publication Number WO/2024/018350
Publication Date 25.01.2024
International Application No. PCT/IB2023/057257
International Filing Date 17.07.2023
Title **
[English] TREATMENT OF AIHA WITH BAFF OR BAFF RECEPTOR INHIBITORY ANTIBODIES
[French] TRAITEMENT DE L'AHAI AVEC DES ANTICORPS INHIBITEURS DE BAFF OU DE RÉCEPTEUR DE BAFF
Applicants **
NOVARTIS AG
Inventors
BEZLYAK, Vladimir
LAWNICZEK, Tomasz
MARTURANO, Emerenziana
STANKOVIC, Miona
URBAN, Patrick
Priority Data
63/368,825   19.07.2022   US
63/384,051   16.11.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4596
EPO Filing, Examination, Granting87995
Japan Filing, Examination, Granting4762
South Korea Filing, Examination, Granting7212
USA Filing, Examination, Granting20340
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Total: 124,905

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The disclosure relates to a molecule that inhibits BAFF pathway, particularly an antibody or a binding fragment thereof, particularly an anti-BAFF-R antibody, e.g. ianalumab, for use in the treatment of autoimmune hemolytic anemia (AIHA), in particular, warm autoimmune hemolytic anemia (wAIHA).[French] L'invention concerne une molécule qui inhibe la voie BAFF, en particulier un anticorps ou un fragment de liaison de celui-ci, en particulier un anticorps anti-BAFF-R, par exemple l'ianalumab, destinée à être utilisée dans le traitement de l'anémie hémolytique auto-immune (AHAI), en particulier, de l'anémie hémolytique auto-immune à anticorps chauds (AHAI-AC).

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