WO2023233339 - COMPOSITIONS AND METHODS FOR DIFFERENTIATING STEM CELLS INTO NK CELLS
National phase entry is expected:
Publication Number
WO/2023/233339
Publication Date
07.12.2023
International Application No.
PCT/IB2023/055613
International Filing Date
01.06.2023
Title **
[English]
COMPOSITIONS AND METHODS FOR DIFFERENTIATING STEM CELLS INTO NK CELLS
[French]
COMPOSITIONS ET PROCÉDÉS DE DIFFÉRENCIATION DE CELLULES SOUCHES EN CELLULES NK
Applicants **
CRISPR THERAPEUTICS AG
Inventors
KYRYCHENKO, Viktoriia
LIAO, Meichen
Priority Data
63/347,989
01.06.2022
US
63/356,985
29.06.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 5911 | |
| EPO | Filing, Examination, Granting | 79961 | |
| Japan | Filing, Examination, Granting | 4408 | |
| South Korea | Filing, Examination, Granting | 6571 | |
| USA | Filing, Examination, Granting | 20540 |
Total:
117,391
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The disclosure features methods and compositions for differentiating stem cells into hematopoietic stem and progenitor cells (HSPC) and/or Natural Killer (NK) cells. The methods and compositions described herein are used to differentiate stem or progenitor cells having at least one gene-edit that is maintained in the differentiated cell. Also provided are differentiated cells produced using the methods and compositions described herein for therapeutic applications.[French]
L'invention concerne des procédés et des compositions pour différencier des cellules souches en cellules souches et progénitrices hématopoïétiques (HSPC) et/ou en cellules tueuses naturelles (NK). Les procédés et les compositions de l'invention sont utilisés pour différencier des cellules souches ou progénitrices ayant au moins une édition de gène qui est maintenue dans la cellule différenciée. L'invention concerne également des cellules différenciées produites à l'aide des procédés et des compositions décrits ici pour des applications thérapeutiques.