WO2023144750 - COMBINATION THERAPY FOR TREATING HEPATITIS B VIRUS INFECTIONS

National phase entry:
Publication Number WO/2023/144750
Publication Date 03.08.2023
International Application No. PCT/IB2023/050687
International Filing Date 26.01.2023
Title **
[English] COMBINATION THERAPY FOR TREATING HEPATITIS B VIRUS INFECTIONS
[French] POLYTHÉRAPIE POUR LE TRAITEMENT D'INFECTIONS PAR LE VIRUS DE L'HÉPATITE B
Applicants **
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
Inventors
DELAHAYE, Jared Loren
LEIVERS, Martin R.
OKOUR, Malek
YOU, Shihyun Kieffer
Priority Data
63/304,091   28.01.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2195
EPO Filing, Examination, Granting9685
Japan Filing, Examination, Granting2232
South Korea Filing, Examination, Granting2174
USA Filing, Examination, Granting5940
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Total: 22,226

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Abstract[English] The present disclosure is related to methods for treating hepatitis B infections. The methods comprising administering a subject in need thereof a PAPD5/7 inhibitor and a modified ASO that targets HBV mRNAs.[French] La présente invention concerne des méthodes de traitement d'infections par l'hépatite B. Les méthodes consistent à administrer, à un sujet en ayant besoin, un inhibiteur de PAPD5/7 et un ASO modifié qui cible les ARNm du VHB.

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