WO2023144747 - HIGH-THROUGHPUT ASSAY FOR CELL MIGRATION, CHEMOTAXIS, AND FUNCTION
National phase entry:
Publication Number
WO/2023/144747
Publication Date
03.08.2023
International Application No.
PCT/IB2023/050684
International Filing Date
26.01.2023
Title **
[English]
HIGH-THROUGHPUT ASSAY FOR CELL MIGRATION, CHEMOTAXIS, AND FUNCTION
[French]
DOSAGE À HAUT DÉBIT POUR MIGRATION CELLULAIRE ET CHIMIOTAXIE ET FONCTION ASSOCIÉE
Applicants **
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
Inventors
GRANDHI, Taraka Sai Pavan
CHENG, Aaron Tien-Hsin
EKERT, Jason Elliot
ROH, Terrence Taelim
Priority Data
63/304,083
28.01.2022
US
63/438,945
13.01.2023
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2596 | |
| EPO | Filing, Examination, Granting | 14131 | |
| Japan | Filing, Examination, Granting | 2480 | |
| South Korea | Filing, Examination, Granting | 2714 | |
| USA | Filing, Examination, Granting | 5740 |
Total:
27,661
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Contact Us
Abstract[English]
An assay system permits study of cell migration through tissue-relevant extracellular matrices under a chemokine gradient within a modular assay platform. Activated CD3+ T-cells were detected, quantified, and studied as they migrated towards chemokines (CXCL10 and CXCL12) and chemokine mimetics (CXCR3 agonist) using the assay system. Discovery of drugs, and the study of microenvironments, stimuli, and responding cells are facilitated by the assay system.[French]
Un système de dosage permet l'étude de la migration cellulaire au moyen de matrices extracellulaires pertinentes pour les tissus exposées à un gradient de chimiokine dans une plateforme de dosage modulaire. Les lymphocytes T CD3+ activés sont détectés, quantifiés et étudiés à mesure qu'ils migrent vers des chimiokines (CXCL10 et CXCL12) et des mimétiques de chimiokine (agoniste de CXCR3) à l'aide du système de dosage. La découverte de médicaments, et l'étude de micro-environnements, de stimuli et de cellules répondeuses sont facilitées par le système de dosage.