WO2023144685 - DETECTION OF PROXIMITY ASSAY PRODUCTS IN SITU
National phase entry:
Publication Number
WO/2023/144685
Publication Date
03.08.2023
International Application No.
PCT/IB2023/050563
International Filing Date
24.01.2023
Title **
[English]
DETECTION OF PROXIMITY ASSAY PRODUCTS IN SITU
[French]
DÉTECTION IN SITU DE PRODUITS DE DOSAGE DE PROXIMITÉ
Applicants **
MOLECULENT AB
Inventors
ERICSSON, Olof John
ROOS, Fredrik
Priority Data
63/303,348
26.01.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2463 | |
| EPO | Filing, Examination, Granting | 14254 | |
| Japan | Filing, Examination, Granting | 2513 | |
| South Korea | Filing, Examination, Granting | 2729 | |
| USA | Filing, Examination, Granting | 5940 |
Total:
27,899
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
This disclosure provides an in situ proximity assay. In some embodiments, the method may comprise (a) performing a proximity assay on one or more pairs of binding agent- oligonucleotide conjugates that are bound to the sample, in situ, to produce proximity assay reaction products; and (b) labeling the sites in the sample at which the proximity assay reaction products are produced, wherein the labeling comprises hybridizing an oligonucleotide to the proximity assay reaction products and does not involve primer extension.[French]
La présente invention propose un dosage de proximité in situ. Dans certains modes de réalisation, le procédé peut comprendre (a) la réalisation d'un dosage de proximité sur une ou plusieurs paires de conjugués agent de liaison-oligonucléotide qui sont liés à l'échantillon, in situ, pour produire des produits de réaction de dosage de proximité ; et (b) le marquage des sites dans l'échantillon au niveau duquel les produits de réaction de dosage de proximité sont produits, le marquage comprenant l'hybridation d'un oligonucléotide aux produits de réaction de dosage de proximité et n'impliquant pas d'extension d'amorce.