WO2023144630 - SINGLE-BEAD CAPACITIVE DETECTOR FOR MICROBIOLOGICAL APPLICATIONS
National phase entry:
Publication Number
WO/2023/144630
Publication Date
03.08.2023
International Application No.
PCT/IB2023/000046
International Filing Date
27.01.2023
Title **
[English]
SINGLE-BEAD CAPACITIVE DETECTOR FOR MICROBIOLOGICAL APPLICATIONS
[French]
DÉTECTEUR CAPACITIF À BILLE UNIQUE POUR APPLICATIONS MICROBIOLOGIQUES
Applicants **
ALTRATECH LIMITED
Inventors
DALTON, Tara
CUMMINS, Timothy
AHERNE, Margaret
MCGUIRE, David
O'DRISCOLL, John
KING, Colin
FREE, Paul
O'FARRELL, Brian
Priority Data
63/304,312
28.01.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3446 | |
| EPO | Filing, Examination, Granting | 35537 | |
| Japan | Filing, Examination, Granting | 3582 | |
| South Korea | Filing, Examination, Granting | 5168 | |
| USA | Filing, Examination, Granting | 11940 |
Total:
59,673
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present invention provides an improved capacitive bead sensor for detection and/or quantification of target analytes in a sample, with a detection limit down to single-beads, which is re-usable for multiple bead tests, or for a continuous flow of beads, and which is easily manufacturable and automatable. It enables sensitivity down to single molecule detection without the need for enzymatic amplification such as PCR, by use of various structural advantages and electronic signal amplification techniques that further allow for multiplex target detection not only across various nucleic acid targets but across entire target classes allowing for simultaneous detection of viral nucleic acids and host antibodies to that virus for example.[French]
La présente invention concerne un capteur à billes capacitif amélioré pour la détection et/ou la quantification d'analytes cibles dans un échantillon, avec une limite de détection jusqu'à des billes uniques, qui est réutilisable pour de multiples tests de billes, ou pour un flux continu de billes, et qui est facile à fabriquer et automatisable. Il permet une sensibilité allant jusqu'à une détection de molécule unique sans avoir besoin d'une amplification enzymatique telle qu'une PCR, par l'utilisation de divers avantages structuraux et de techniques d'amplification de signal électronique qui permettent en outre une détection de cible multiplex non seulement au niveau de diverses cibles d'acide nucléique mais au niveau de classes de cibles entières permettant la détection simultanée d'acides nucléiques viraux et d'anticorps hôtes à ce virus par exemple.