WO2023126798 - CAPILLARY ELECTROPHORESIS OF ENCAPSULATED RNA

National phase entry:
Publication Number WO/2023/126798
Publication Date 06.07.2023
International Application No. PCT/IB2022/062699
International Filing Date 22.12.2022
Title **
[English] CAPILLARY ELECTROPHORESIS OF ENCAPSULATED RNA
[French] ÉLECTROPHORÈSE CAPILLAIRE D'ARN ENCAPSULÉ
Applicants **
DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
Inventors
GUTIERREZ, Mervin
Priority Data
63/295,029   30.12.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2558
EPO Filing, Examination, Granting16582
Japan Filing, Examination, Granting2656
South Korea Filing, Examination, Granting3049
USA Filing, Examination, Granting6940
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Total: 31,785

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Abstract[English] The presently claimed and described technology provides methods for analyzing an encapsulated biomolecule by loading the encapsulated biomolecule on a capillary electrophoresis (CE) capillary, wherein the CE capillary is filled with a buffer comprising a polymer matrix; applying a voltage to the CE capillary to release the biomolecule from the encapsulating material; and detecting the biomolecule released from the encapsulating material. Kits for analyzing an encapsulated biomolecule are also disclosed.[French] L’invention concerne des procédés d'analyse d'une biomolécule encapsulée par chargement de la biomolécule encapsulée sur un capillaire d’électrophorèse capillaire (CE), le capillaire CE étant rempli d'un tampon comprenant une matrice polymère ; l’application d'une tension au capillaire CE pour libérer la biomolécule à partir du matériau d'encapsulation ; et de détection de la biomolécule libérée à partir du matériau d'encapsulation. L'invention concerne également des kits d'analyse d'une biomolécule encapsulée.

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