WO2023112000 - AN IMPROVED METHOD FOR SEPARATION OF LOW MOLECULAR WEIGHT PROTEINS

National phase entry:
Publication Number WO/2023/112000
Publication Date 22.06.2023
International Application No. PCT/IB2022/062426
International Filing Date 17.12.2022
Title **
[English] AN IMPROVED METHOD FOR SEPARATION OF LOW MOLECULAR WEIGHT PROTEINS
[French] PROCÉDÉ AMÉLIORÉ DE SÉPARATION DE PROTÉINES DE FAIBLE POIDS MOLÉCULAIRE
Applicants **
KASHIV BIOSCIENCES, LLC
Inventors
UPADHYAY, Roshan Ganeshlal
KARDANI, Jaykumar Rameshchandra
SHAH, Aakansha
Priority Data
202121058987   17.12.2021   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2013
EPO Filing, Examination, Granting11598
Japan Filing, Examination, Granting2076
South Korea Filing, Examination, Granting1928
USA Filing, Examination, Granting4310
MasterCard Visa
Total: 21,925

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present invention provides the method for the separation of at least more than two Low molecular weight (LMWs) impurities present in the protein mixture comprising fusion protein CTL4-IgG1 by using Capillary Electrophoresis-Sodium dodecyl sulfate (CE-SDS) wherein the loading amount of protein mixture is more than 270 µg. The invention further provides a ratio of protein to sodium dodecyl sulfate is 2.7:1 or higher.[French] La présente invention concerne le procédé de séparation d'au moins plus de deux impuretés de faible poids moléculaire (LMW) présentes dans le mélange de protéines comprenant la protéine de fusion CTL4-IgG1 en utilisant du dodécylsulfate de sodium d'électrophorèse capillaire (CE-SDS), la quantité de charge du mélange de protéines étant supérieure à 270 µg. L'invention concerne en outre un rapport entre la protéine et le dodécylsulfate de sodium supérieur ou égal à 2,7 : 1.

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